She has a loving family and best friends, laughs and cries from time to time... Madoka Kaname, an eighth grader of Mitakihara middle school, is one of those who lives such a life. One day, she had a very magical encounter. She doesn't know if it happened by chance or by fate yet. This is a fateful encounter that can change her destiny. This is a beginning of the new story of the magical witch girls.

Koyomi Araragi, a high school student, finds himself constantly encountering girls afflicted by supernatural "oddities." He dedicates himself to helping them, often with the aid of the eccentric specialist Meme Oshino. Each arc talks about a different girl's unique struggle and the mysterious cause of their affliction. The series explores themes of adolescence, personal growth, and the complexities of human relationships. It's known for its witty dialogue, stylistic animation, and unique narrative structure.

In a world where memories can be stored like computer data, a young man named Kaiba searches for his lost memories and discovers a connection with a mysterious girl.